A region and availability zone (AZ) identify the location of a data center. You can create resources in a specific region and AZ.
Figure 1 shows the relationship between regions and AZs.
Figure 1 Regions and AZs

You are advised to select a region close to you or your target users. This reduces network latency and improves access speed.
When determining whether to deploy resources in the same AZ, consider your applications' requirements for disaster recovery (DR) and network latency.
Before using an API to call resources, you must specify its region and endpoint. For details about regions and endpoints, see Regions and Endpoints.